What Happens to Your Body and Brain When You Combine Different Drugs?

Speed, cocaine and Adderall energize the nervous system and escalate heart rate. LSD can also increase your heart rate, putting extra strain on your cardiovascular system, which could put you at risk for heart attack or stroke. This may not be an issue at manageable doses, but you may end up doing more of a drug than you intended.

Use the minimum dose required to achieve your desired effect, stay in a safe environment with people you trust, and avoid mixing with alcohol and prescription medication. Cannabis can have a profoundly distinct impact when taken concurrently unique sobriety gifts with psilocybin. In 2019 the pro-psychedelic publication Double Blind surveyed 90 people who reported combining cannabis and psychedelics. The publication also interviewed medical experts who could speak to the effects of combining cannabis and psychedelics.

Another barrier to understanding possible drug interactions is that MDMA works on multiple systems in the body – increasing the chances reese witherspoon fetal alcohol syndrome for additive, synergistic and/or antagonistic interactions when combined with other substances. But the possible risks outweigh the benefits when people combine the drugs. Exercise caution when using marijuana or MDMA, and start with low doses until you understand your tolerance levels. There is a clear overlap of pharmacology between cannabis and psychedelics. Both are being considered as novel treatments for conditions that currently lack adequate effective therapies like anxiety, depression, and PTSD.

This drug is famous for being used at parties, raves, or nightclubs as a primary drug of misuse. People who misuse ecstasy are more likely to engage in polydrug use, including marijuana. Like cannabis, MDMA is a Schedule I controlled substance at the federal level in the United States.

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Combining more than one from each of those boxes can increase your risk,” says Dr. Owen Bowden-Jones, founder of the CNWL Drug Club Clinic. The FHE Health team is committed to providing accurate information that adheres to the highest standards of writing. If one of our articles is marked with a ‘reviewed for accuracy and expertise’ badge, it indicates that one or more members of our team of doctors and clinicians have reviewed the article further to ensure accuracy. This is part of our ongoing commitment to ensure FHE Health is trusted as a leader in mental health and addiction care. MDMA, more commonly referred to as ecstasy or Molly, is a synthetic drug that is both a stimulant and a hallucinogen.

However, this doesn’t mean that it can’t cause unpleasant effects when taken in large doses. Marijuana use can cause paranoia, trouble thinking, impulsive decision-making, and, in rare cases, a form of acute psychosis that includes hallucinations and delusions. Marijuana is a plant found organically in nature that can be smoked or ingested via edibles.

1. It is commonly used in hospital emergency departments and operating rooms to produce profound sedation.
2. However, it does create a whole new different kind of high in itself, which is possibly why so many people end up reaching for their phones once they’ve got a few beers inside them.
3. Because use feels different in numerous ways, including a longer high or a longer period before a high set in, users may find themselves inadvertently taking larger doses than intended.
4. “Smoking cannabis on LSD seems to potentiate the effects of both, so you end up with a sort of stronger effect of both substances,” said Gomez.
5. While we eagerly wait to see the results of new research into cannabis and psychedelics, and their combinations and interactions, caution is advised.
6. However, this doesn’t mean that it can’t cause unpleasant effects when taken in large doses.

It was dubbed “molly” because the acronym MDMA can be challenging to say, and “ecstasy” for its intense euphoric effects. Its popularity surged as it made its way deep into the party and rave scenes, prompting the US government to make it illegal in 1985. The stimulant aspect of MDMA gives users a jolt of energy much more intense than a strong cup of coffee. The hallucinogenic aspect of the drug can make MDMA users feel euphoric while also leading to hallucinations and distortions of the experiences of time and space. A 2012 research paper published in the Journal of Clinical Anaesthesia found that combining ketamine and cannabis resulted in a further reduction of pain.

What Happens to Your Body and Brain When You Combine Different Drugs?

This includes ayahuasca, peyote cactus, hallucinogenic mushrooms, and Salvia Divinorum. The term psychedelic is derived from the Greek words ‘ψυχή (psyche, or mind), and ‘δηλείν’ (delein, to reveal). Today these terms are used to denote a class of drugs known for their mind-altering abilities. Another major issue with mixing any illegal drug is knowing what it actually is.

Tripping: Combining Drugs

With that in mind, the more crack you use, the more heroin you’re going to use to balance yourself out, raising the risk of overdose. In fact, polysubstance use—a grand term for “getting fucked up with more than one drug”—tends to be the norm rather than the exception for most drug users. If you or a loved one are missing marijuana and ecstasy and need help, we are here for you. Our inpatient rehab near Tampa offers several different types of addiction treatment that can get you started on the road to recovery.

LSD and other psychedelics

If you are in a crisis or if you or any other person may be in danger or experiencing a mental health emergency, immediately games for substance abuse groups call 911 or your local emergency resources. If you are considering suicide, please call 988 to connect with the National Suicide Prevention Lifeline. You can, of course, test your drugs at home using kits you can purchase online but they may not always identify all the present compounds. Or, if you’re feeling science-y and can wait a few weeks, you can mail a drug sample to EcstasyData.org, an organization supported by DanceSafe. It helps to ask about doses and purity from your drug connection, but even they may not know what they’re selling.